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Peptides

From which links is there a peptide and how can you get peptides organize? In this article we will tell you what a peptide is, how it is built up and how you can classify them according to the number of their amino acids.

Also take a look at our Video if you want to have the peptides explained quickly and easily.

Peptide explained simply

Basically, a peptide is an off amino acids constructed molecule. So-called peptide bonds link these amino acids to form large chains. You can classify these peptides depending on Number of amino acidsfrom which they are built and the larger the peptide chain becomes. Peptides are found in all organisms and have different functions. Among other things, they can be used as Neurotransmitters, Peptide hormone or as Antibiotics occur.

structure

Peptides form in one Condensation reaction the – Carboxy group () one amino acid and the – Amino group () another amino acid.

Our article on Peptide bond gives you an overview of this connection and defines the meaning of .

The resulting Acid amide grouping () (=Peptide group) is characteristic of a peptide. The free Carboxy group at the end of the petid is shown as C-terminus and the free Amino group on the other end than N-terminus designated.

Depending on how long this chain of amino acids is, you can divide a peptide into different areas.

Dipeptide

Dipeptides are made from two amino acid residues composed. A dipeptide is named on the basis of the two amino acids. When both amino acids identical are, the name of the amico acid becomes the name prefixed: Alanylalanine, Serylserine. If you have different amino acids, you first have to match the amino acid with the free carboxy group looking for the C-terminus. This provides you with the Tribe names for your connection. The Amino acid residue with the N-terminus becomes that name prefixed. A combination of the amino acids glycine (Gly) and alanine (Ala) can produce the dipeptide alanylglycine (Ala-Gly) or glycylalanine (Gly-Ala).

The dipeptides are usually created in the body as Intermediates in the enzymatically controlled digestion of proteins.

Tripeptide

Tripeptides basically consist of a compound of three amino acid residues. The naming is similar to the dipeptides, in that the C-terminal amino acid is used as the stem name and the N-terminal amino acid is prefixed. The third amino acid is used in naming between assigned to these two other amino acids. The exemplary tripeptide glutathione (= glutamylcysteinylglycine) consists of the three amino acids glutamic acid, cysteine ​​and glycine.

Oligopeptide

An oligopeptide can be used to describe peptides that are caused by less than ten amino acids are linked. Thus, the dipeptides and the tripeptides also belong to the oligopeptides. They mostly play a role in our body as enzymes Detox- or Metabolic processes a role.

Cyclopeptide

A circular peptide is called Cyclopeptide or Lactam designated. Cyclopeptides, which consist of two rings, can be called bicyclic peptides. Well-known representatives of this group are Phalloidin and the Amanitin